2025 UK HIV and the CNS Day
- Friday, 28th March 2025
- Arundel House, Six Temple Place, London WC2R 2PG
| Time | Topic | Speaker | Chair(s) | |
|---|---|---|---|---|
| 0845 – 0915 | Arrival and Coffee | |||
| 0915 – 0930 | Welcome | Alan Winston (Imperial, UK) | ||
| 0930 – 1100 | Session 1: Plenary talks | |||
| 0930 – 1000 | Sleep Science and relevance to HIV | Malcolm von Schantz (Northumbria, UK) | Alan Winston, Alex Everitt | |
| 1000 – 1030 | Effects of ART on the brain | Aylin Yilmaz (Gothenburg, Sweden) | Alan Winston, Alex Everitt | |
| 1030 – 1100 | Discussion | |||
| 1100 – 1130 | Morning Coffee | |||
| 1130 – 1245 | Session 2: Case and Research Presentations | |||
| 1130 – 1145 | Pregnancy and Cryptococcal Meningitis | Tamzin Hull (King’s College Hospital) | Jo Josh, Liz Hamlyn, Nick Davies | |
| 1145 – 1200 | A Paradoxical IRIS | Maeve Barlow (Mortimer Market Centre) | Jo Josh, Liz Hamlyn, Nick Davies | |
| 1200 – 1215 | Neuronal Biomarker Changes | Merle Henderson (Imperial College London) | Jo Josh, Liz Hamlyn, Nick Davies | |
| 1215 – 1245 | Discussion | |||
| 1245 – 1400 | Lunch | |||
| 1400 – 1530 | Session 3: Plenary Talks | |||
| 1400 – 1430 | Clinical assessment of cognitive symptoms | Shibani Mukerji (Harvard Medical School, USA) | Jaime Vera, Monica Marta,Anton Pozniak | |
| 1430 – 1500 | The Early Initiation of ART and impact on the CNS | Serena Spudich (Yale, USA) | Jaime Vera, Monica Marta,Anton Pozniak | |
| 1500 – 1530 | Discussion | |||
| 1530 – 1545 | Afternoon Coffee | |||
| 1545 – 1700 | Session 4: Cases and Research Presentations | |||
| 1545 – 1600 | Blindness, deafness and pachymeningitis | Hao Wen Gerald Gan (King’s College Hospital) | Memory Sachikonye, Simon Rackstraw, Hadi Manji | |
| 1600 – 1615 | Disseminated MAC and Ophthalmoplegia | Niroshan Dayalan (Chelsea and Westminster Hospital) | Memory Sachikonye, Simon Rackstraw, Hadi Manji | |
| 1615 – 1630 | Addressing cognitive symptoms in people with HIV | Katie Alford (Brighton and Sussex Medical School) | Memory Sachikonye, Simon Rackstraw, Hadi Manji | |
| 1630 – 1700 | Discussion | |||
| 1700 - | Feedback, awards, summary and close | Alan Winston, Jo Josh and Memory Sachikonye |
This is an independent meeting which is kindly supported by Gilead Sciences, ViiV Healthcare and MSD. No sponsor has any control over content of the meeting.
The meeting is approved for 6 CPD credits by the Federation of the UK Royal College of Physicians: code 150545
Guest speakers:
-
Malcolm von Schantz (Northumbria, UK) Sleep Science and Relevance to HIV
Malcolm von Schantz is a human chronobiologist received his training in Sweden, the United States, and the UK. He joined Northumbria University in 2021 from the University of Surrey, where he also served in leaderships positions as Associate Dean (International) and acting Pro-Vice Chancellor (International Relations). His research focuses on sleep and sleep timing as a global health issue. He is interested in how human circadian rhythms and sleep are affected by genetic and environmental factors and how they influence physical and mental health outcomes. His work is currently funded by the MRC and the Wellcome Trust.
-
Shibani Mukerji (Harvard Medical School, USA) Clinical assessment of cognitive symptoms
Shibani Mukerji, MD/Ph.D., is the Associate Director of the Neurology Infectious Diseases Unit at Massachusetts General Hospital (MGH) and an Associate Professor of Neurology at Harvard Medical School. Dr. Mukerji brings a clinical focus on improving neurological outcomes, enhancing high-quality care, and reducing healthcare costs for individuals with HIV. She is a Principal Investigator for the SOOTHE study, a Phase II clinical trial evaluating the role of pregnenolone on brain function and immune responses in people with HIV and depression, and co-PI for the BEACON study which examines the HIV-1 reservoir in central nervous system tissue. She earned her M.D. and Ph.D. from Case Western Reserve University, completed neurology residency and neurology-infectious diseases post-doctoral training at MGH and Brigham and Women's Hospital.
-
Aylin Yilmaz (Gothenburg, Sweden) Effects of ART on the brain
Aylin Yilmaz is a consultant and Senior Lecturer in infectious disease at the University of Gothenburg. She is the lead clinician for the HIV department. Her research focuses on central nervous system manifestations of different infectious diseases, specifically HIV and SARS-CoV-2. Aylin has published widely on cerebrospinal fluid exposure of different antiretroviral agents and soluble biomarkers in the CSF.
-
Serena Spudich (Yale, USA) The Early Initiation of ART and impact on the CNS
Serena is Gilbert H. Glaser Professor of Neurology and Chief, Division of Neurological Infections and Global Neurology at Yale University. Her clinical and translational research explores effects of HIV and other viral infections in the nervous system, focusing on effects of acute infection, antiviral and immune treatments, and cure strategies on viral pathogenesis and persistence in the central nervous system (CNS). She collaborates with colleagues of multiple disciplines in studies in the United States and in international settings, exploring questions of inflammation, injury, and viral reservoirs within the central nervous system. She has been active in the AIDS Clinical Trials Group (ACTG) Neurology and HIV Reservoirs and Eradication committees, co-leads the International NeuroHIV Cure Consortium, serves on the US DHHS Antiretroviral Treatment Guidelines Committee, CROI Program Committee, and leads multidisciplinary projects addressing the pathobiology of HIV and SARS-CoV-2 in the CNS.